The Early Changes in the Axoplasm during Wallerian Degeneration

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The Early Changes in the Axoplasm during Wallerian Degeneration

Axoplasmic changes were studied in the saphenous nerve of the albino rat during the early stages of Wallerian degeneration. The axons were examined at 0, 24, and 48 hours after the surgical transection of the nerve. The material was fixed in 2 per cent OsO(4) in phosphate buffer (pH 7.2-7.5) with sucrose (added to a final osmolar concentration of approximately 0.37 M). The earliest changes were...

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The Early Changes in the Axoplasm during WaUerian Degeneration

Axoplasmic changes were studied in the saphenous nerve of the albino rat during the early stages of Wallerian degeneration. The axons were examined at 0, 24, and 48 hours after the surgical transection of the nerve. The material was fixed in 2 per cent OsO4 in phosphate buffer (pH 7.2-7.5) with sucrose (added to a final osmolar concentration of ~0.37 ~a). The earliest changes were seen in the e...

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Conduction in the lateral popliteal nerve of the baboon was studied during the course of Wallerian degeneration. Six nerves were examined. In each case the muscle response to nerve stimulation and the ascending nerve action potential were recorded daily until the nerve became inexcitable. The muscle response to nerve stimulation disappeared after four to five days, but ascending nerve action po...

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ژورنال

عنوان ژورنال: The Journal of Biophysical and Biochemical Cytology

سال: 1958

ISSN: 1540-8140,0021-9525

DOI: 10.1083/jcb.4.5.551